Metformin

  • CAT Number: R039773
  • CAS Number: 657-24-9
  • Molecular Formula: C4H11N5
  • Molecular Weight: 129.167
  • Purity: ≥95%
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Metformin(CAT: R039773) is a diabetes drug. It can inhibit the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity in type 2 diabetes studies. This product is used for organic synthesis, pharmaceutical research and development, and other scientific purposes.

Catalog Number R039773
CAS Number 657-24-9
Molecular Formula

C4H11N5

Purity 95%
Storage 3 years -20C powder
IUPAC Name 3-(diaminomethylidene)-1,1-dimethylguanidine
InChI InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)
InChIKey XZWYZXLIPXDOLR-UHFFFAOYSA-N
SMILES CN(C)C(=N)N=C(N)N
Reference

<p>
<span style=”color:#000000;”><span style=”font-size:12px;”><span style=”font-family:arial,helvetica,sans-serif;”>1.Soraya, Hamid, et al. &quot;Acute treatment with metformin improves cardiac function following isoproterenol induced myocardial infarction in rats.&quot;&nbsp;<i style=”font-family: Arial, sans-serif; font-size: 13px;”>Pharmacological Reports</i>&nbsp;64.6 (2012): 1476-1484.<br />
2.Quaile, Michael P., et al. &quot;Toxicity and toxicokinetics of metformin in rats.&quot;&nbsp;<i style=”font-family: Arial, sans-serif; font-size: 13px;”>Toxicology and applied pharmacology</i>&nbsp;243.3 (2010): 340-347.<br />
3.Xue, Jing, et al. &quot;Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment of adenomyosis.&quot;&nbsp;<i style=”font-family: Arial, sans-serif; font-size: 13px;”>Reproduction</i>&nbsp;146.4 (2013): 397-406.</span></span></span></p>

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