MDK6620

• CAT Number: I031750
• CAS Number: 304456-62-0
• Molecular Formula: C12H9BrN2OS
• Molecular Weight: 309.18
• Purity: 98%
• Solubility: Soluble in DMSO
• Storage: 4°C, protect from light
• IUPAC Name: 2-[[(5-bromo-2-thienyl)methylene]amino]-benzamide
• InChI: InChI=1S/C12H9BrN2OS/c13-11-6-5-8(17-11)7-15-10-4-2-1-3-9(10)12(14)16/h1-7H,(H2,14,16)/b15-7+
• InChIKey: OZEADOPONHLEDS-VIZOYTHASA-N
• SMILES: O=C(N)C1=CC=CC=C1/N=C/C2=CC=C(Br)S2

MDK6620（Cat No.:I031750）, also referred to as BTYNB IMP1 Inhibitor is a compound that acts as an inhibitor of the oncofetal mRNA-binding protein IMP1. It displays an inhibitory effect on the binding of IMP1 to c-Myc mRNA, with an IC50 value of 5 μM. By targeting IMP1, MDK6620 potentially disrupts the interaction between IMP1 and c-Myc mRNA, which may have implications in cancer-related processes. Further research is necessary to explore the therapeutic potential of MDK6620 in cancer treatment and its impact on IMP1-mediated functions.

Reference

1. L. Mahapatra, N. Andruska, C. Mao, et al. A novel IMP1 inhibitor, BTYNB, targets c-Myc and inhibits melanoma and ovarian cancer cell proliferation. Transl. Oncol. 10(5), 818-827 (2017).