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Mcl1-IN-8

Mcl1-IN-8

  • CAT Number: I018146
  • CAS Number: 678158-55-9
  • Molecular Formula: C₂₂H₂₃N₃O₂S
  • Molecular Weight: 393.5
  • Purity: ≥95%
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Mcl1-IN-8 (Cat.No:I018146) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells.

Catalog Number I018146
CAS Number 678158-55-9
Molecular Formula

C₂₂H₂₃N₃O₂S

Purity 95%
Reference

[1]. Liu J, et al. Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound. Oncotarget. 2017 Apr 20;8(33):54236-54242.

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