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Mannide Monooleate

Mannide Monooleate

  • CAT Number: M009982
  • CAS Number: 9049-98-3
  • Molecular Formula: C24H44O7
  • Molecular Weight: 444.609
  • Purity: ≥95%
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Mannide Monooleate is an emulsifying agent utilized in Freund′s incomplete adjuvant.

Catalog Number M009982
CAS Number 9049-98-3
Molecular Formula

C24H44O7

Purity 95%
Storage Store at RT
IUPAC Name [(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (Z)-octadec-9-enoate
InChI InChI=1S/C24H44O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(26)31-24-23(29)22(28)21(27)19(18-25)30-24/h9-10,19,21-25,27-29H,2-8,11-18H2,1H3/b10-9-/t19-,21-,22+,23+,24?/m1/s1
InChIKey LUXUAZKGQZPOBZ-SAXJAHGMSA-N
SMILES CCCCCCCCC=CCCCCCCCC(=O)OC1C(C(C(C(O1)CO)O)O)O
Reference

1: O/’Neill HJ, Yamauchi TN, Cohen P, Hardegree MC. Characterization of mannide
monooleate. J Pharm Sci. 1972 Jun;61(6):863-7. PubMed PMID: 5046100.

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2: Hardegree MC, Pittman M. Influence of antigens on release of free fatty acids
from Arlacel A (mannide monooleate). Proc Soc Exp Biol Med. 1966
Oct;123(1):179-84. PubMed PMID: 5332443.

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3: Ricciardi A, Visitsunthorn K, Dalton JP, Ndao M. A vaccine consisting of
Schistosoma mansoni cathepsin B formulated in Montanide ISA 720 VG induces high
level protection against murine schistosomiasis. BMC Infect Dis. 2016 Mar
5;16:112. doi: 10.1186/s12879-016-1444-z. PubMed PMID: 26945988; PubMed Central
PMCID: PMC4779570.
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4: Rodrigues L, Kyriakos K, Schneider F, Dietz H, Winter G, Papadakis CM, Hubert
M. Characterization of Lipid-Based Hexosomes as Versatile Vaccine Carriers. Mol
Pharm. 2016 Nov 7;13(11):3945-3954. Epub 2016 Sep 27. PubMed PMID: 27607892.

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5: Burns JM Jr, Miura K, Sullivan J, Long CA, Barnwell JW. Immunogenicity of a
chimeric Plasmodium falciparum merozoite surface protein vaccine in Aotus
monkeys. Malar J. 2016 Mar 15;15:159. doi: 10.1186/s12936-016-1226-5. PubMed
PMID: 26975721; PubMed Central PMCID: PMC4791798.

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