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Mal-PEG1-acid

Mal-PEG1-acid

  • CAT Number: I017122
  • CAS Number: 760952-64-5
  • Molecular Formula: C₉H₁₁NO₅
  • Molecular Weight: 213.19
  • Purity: ≥95%
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Mal-PEG1-acid (Cat.No:I017122) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Catalog Number I017122
CAS Number 760952-64-5
Molecular Formula

C₉H₁₁NO₅

Purity 95%
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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