m-PEG7-thiol

  • CAT Number: I015084
  • CAS Number: 651042-82-9
  • Molecular Formula: C₁₅H₃₂O₇S
  • Molecular Weight: 356.48
  • Purity: ≥95%
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m-PEG7-thiol(CAT: I015084) is a versatile PEG-based PROTAC linker designed for use in the synthesis of PROTAC molecules. With its thiol functionality, it enables effective conjugation and linkage of different molecular entities, facilitating the construction of targeted protein degraders. This linker’s polyethylene glycol (PEG) scaffold contributes to improved solubility and biocompatibility, while the thiol group enables efficient coupling reactions. By incorporating m-PEG7-thiol into PROTAC design, researchers can potentially develop innovative therapeutic agents for targeted protein degradation, opening avenues for drug discovery and development in various disease areas.

Catalog Number I015084
CAS Number 651042-82-9
Molecular Formula

C₁₅H₃₂O₇S

Purity 95%
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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