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m-PEG2-Tos

m-PEG2-Tos

  • CAT Number: I017195
  • CAS Number: 50586-80-6
  • Molecular Formula: C₁₂H₁₈O₅S
  • Molecular Weight: 274.33
  • Purity: ≥95%
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m-PEG2-Tos（Cat No.:I017195） is a non-cleavable ADC linker commonly employed in the synthesis of antibody-drug conjugates (ADCs). This linker is designed to stably connect the antibody and the cytotoxic payload, ensuring the controlled release of the drug at the target site. Additionally, m-PEG2-Tos can serve as a linker for PROTAC synthesis. PROTACs are bifunctional molecules that target specific proteins for degradation, and m-PEG2-Tos can facilitate the conjugation of the protein-targeting ligand and the E3 ligase ligand in PROTAC development.

Catalog Number I017195
CAS Number 50586-80-6
Molecular Formula

C₁₂H₁₈O₅S

Purity 95%
Related CAS CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOC
IUPAC Name 2-(2-methoxyethoxy)ethyl 4-methylbenzenesulfonate
InChIKey InChI=1S/C12H18O5S/c1-11-3-5-12(6-4-11)18(13,14)17-10-9-16-8-7-15-2/h3-6H,7-10H2,1-2H3
SMILES PBKGNJXLJQARIN-UHFFFAOYSA-N

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