Lycorine hydrochloride

• CAT Number: I002671
• CAS Number: 2188-68-3
• Molecular Formula: C16H18ClNO4
• Molecular Weight: 323.77
• Purity: ≥95%
• Solubility: DMSO ≥ 31 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (1S,17S,18S,19S)-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,15-tetraene-17,18-diol;hydrochloride
• InChI: InChI=1S/C16H17NO4.ClH/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19;/h3-5,11,14-16,18-19H,1-2,6-7H2;1H/t11-,14-,15+,16+;/m0./s1
• InChIKey: VUVNTYCHKZBOMV-NVJKKXITSA-N
• SMILES: C1CN2CC3=CC4=C(C=C3C5C2C1=CC(C5O)O)OCO4.Cl

Lycorine hydrochloride (Cat.No:I002671) is a natural alkaloid derived from various plants of the Amaryllidaceae family. It possesses a wide range of pharmacological activities, including anticancer, antiviral, and antimalarial properties. Lycorine hydrochloride has been studied for its potential in cancer therapy and as an antiviral agent against viruses such as HIV and hepatitis C.

Reference

[1]. Liu, R. et al. Lycorine hydrochloride inhibits metastatic melanoma cell-dominant vasculogenic mimicry. Pigment cell & melanoma research 25, 630-638, doi:10.1111/j.1755-148X.2012.01036.x (2012).

[2]. Cao, Z. et al.Lycorine hydrochloride selectively inhibits human ovarian cancer cell proliferation and tumor neovascularization with very low toxicity. Toxicology letters 218, 174-185, doi:10.1016/j.toxlet.2013.01.018 (2013).