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LY 78335

LY 78335

  • CAT Number: I010885
  • CAS Number: 39959-66-5
  • Molecular Formula: C8H10Cl3N
  • Molecular Weight: 226.525
  • Purity: ≥95%
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LY 78335(CAT: I010885) is a high-affinity inhibitor of phenylethanolamine-N-methyltransferase (PNMT). PNMT is an enzyme involved in the conversion of norepinephrine to epinephrine, a process important in the synthesis of catecholamines. By inhibiting PNMT, LY 78335 can block the activity of this enzyme and potentially reduce the production of epinephrine. In an in vivo rat model, LY 78335 has been shown to suppress the release of growth hormone.

Catalog Number I010885
CAS Number 39959-66-5
Molecular Formula

C8H10Cl3N

Purity 95%
Target Transferase
Solubility Soluble to 100 mM in water with gentle warming and to 100 mM in DMSO with gentle warming
Storage Desiccate at RT
IUPAC Name 1-(2,3-dichlorophenyl)ethanamine;hydrochloride
InChI InChI=1S/C8H9Cl2N.ClH/c1-5(11)6-3-2-4-7(9)8(6)10;/h2-5H,11H2,1H3;1H
InChIKey FQTXPVLCCDQRHY-UHFFFAOYSA-N
SMILES CC(C1=C(C(=CC=C1)Cl)Cl)N.Cl

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