For research use only. Not for therapeutic Use.
LY-221204 (Cat No.: I007792) is a potent and selective inhibitor targeting tumor necrosis factor-alpha (TNF-α), a key cytokine involved in inflammation and immune responses. It has demonstrated strong anti-inflammatory effects by blocking TNF-α activity, making it a promising candidate for treating autoimmune disorders such as rheumatoid arthritis and inflammatory bowel disease. LY-221204’s high specificity helps minimize off-target effects, enhancing its therapeutic potential. Its unique mechanism of action positions it as a valuable tool in both preclinical research and future drug development efforts.
| CAS Number | 131399-37-6 |
| Synonyms | LY-221204; LY 221204; LY221204.;(E)-4-Chloro-N-(4-chlorophenyl)-2,2-dimethyl-3-butenamide |
| Molecular Formula | C12H13Cl2NO |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term , or -20°C for long term. |
| IUPAC Name | (E)-4-chloro-N-(4-chlorophenyl)-2,2-dimethylbut-3-enamide |
| InChI | InChI=1S/C12H13Cl2NO/c1-12(2,7-8-13)11(16)15-10-5-3-9(14)4-6-10/h3-8H,1-2H3,(H,15,16)/b8-7+ |
| InChIKey | BZXGAFLNIFSHQG-BQYQJAHWSA-N |
| SMILES | CC(C)(C=CCl)C(=O)NC1=CC=C(C=C1)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
