• CAT Number: I004787
  • CAS Number: 1334493-07-0
  • Molecular Formula: C29H27F5N2O6S
  • Molecular Weight: 626.59
  • Purity: ≥95%
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BP-1-102(Cat No.:I004787) is a potent, orally bioavailable and selective STAT3 inhibitor. BP-1-102 binds Stat3 with an affinity (K(D)) of 504 nM, blocks Stat3-phospho-tyrosine (pTyr) peptide interactions and Stat3 activation at 4-6.8 μM, and selectively inhibits growth, survival,migration, and invasion of Stat3-dependent tumor cells.

Catalog Number I004787
CAS Number 1334493-07-0
Molecular Formula


Purity 95%
Target STAT3 inhibitor
Solubility Soluble in DMSO, not in water
Storage -20°C
IUPAC Name 4-[(4-cyclohexylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]-2-hydroxybenzoic acid
InChI InChI=1S/C29H27F5N2O6S/c1-35(43(41,42)28-26(33)24(31)23(30)25(32)27(28)34)15-22(38)36(19-11-12-20(29(39)40)21(37)13-19)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h7-13,17,37H,2-6,14-15H2,1H3,(H,39,40)

</br>1: Zhang X, Yue P, Page BD, Li T, Zhao W, Namanja AT, Paladino D, Zhao J, Chen Y, Gunning PT, Turkson J. Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proc Natl Acad S

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