Loperamide-d6 Hydrochloride

• CAT Number: R005609
• CAS Number: 1189469-46-2
• Molecular Formula: C29H34Cl2N2O2
• Molecular Weight: 519.54
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenyl-N,N-bis(trideuteriomethyl)butanamide;hydrochloride
• InChI: InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H/i1D3,2D3
• InChIKey: PGYPOBZJRVSMDS-TXHXQZCNSA-N
• SMILES: CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

Loperamide-d6 hydrochloride（Cat No.:R005609）, is a deuterium-labeled derivative of loperamide hydrochloride, a medication used to manage symptoms of diarrhea. Deuterium is a stable, non-radioactive isotope of hydrogen, and its incorporation into loperamide allows for the tracing and quantification of the drug’s metabolism and pharmacokinetics in biological systems. Loperamide-d6 hydrochloride is employed in pharmacokinetic studies and bioanalytical research to understand how the drug is absorbed, distributed, metabolized, and eliminated in the body. This isotopic labeling aids researchers in elucidating the drug’s pharmacological properties and can contribute to the development of safer and more effective medications for diarrhea management.