Lofexidine hydrochloride

  • CAT Number: I002649
  • CAS Number: 21498-08-8
  • Molecular Formula: C11H12Cl2N2O • HCl
  • Molecular Weight: 295.6
  • Purity: ≥95%
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<p style=/line-height:25px/>Lofexidine hydrochloride (Cat.No:I002649) is an α2A-adrenergic receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.</p>

Catalog Number I002649
CAS Number 21498-08-8
Molecular Formula

C11H12Cl2N2O • HCl

Purity 95%
Target Adrenergic Receptor
Solubility 10 mM in H2O
Storage Store at -20°C
InChIKey DWWHMKBNNNZGHF-UHFFFAOYSA-N
Reference

</br>1:Pharmacokinetics of lofexidine hydrochloride in healthy volunteers. Al-Ghananeem AM.J Pharm Sci. 2009 Jan;98(1):319-26. doi: 10.1002/jps.21401. PMID: 18393298 </br>2:Randomized placebo controlled trial of lofexidine hydrochloride for chronic pelvic pain in women. Stones RW, Bradbury L, Anderson D.Hum Reprod. 2001 Aug;16(8):1719-21. PMID: 11473971 </br>3:The absorption and excretion of 14C-lofexidine hydrochloride in man. Midgley I, Chasseaud LF, Taylor T, Darragh A.Arzneimittelforschung. 1982;32(8a):972-5. No abstract available. PMID: 6890372

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