LMP7-IN-1

• CAT Number: I019382
• CAS Number: 2285330-15-4
• Molecular Formula: C₁₇H₂₀BNO₅
• Molecular Weight: 329.16
• Purity: ≥95%
• Storage: Store at -20°C
• IUPAC Name: [(1R)-2-(1-benzofuran-3-yl)-1-[[(1S,2R,4R)-7-oxabicyclo[2.2.1]heptane-2-carbonyl]amino]ethyl]boronic acid
• InChI: InChI=1S/C17H20BNO5/c20-17(13-8-11-5-6-15(13)24-11)19-16(18(21)22)7-10-9-23-14-4-2-1-3-12(10)14/h1-4,9,11,13,15-16,21-22H,5-8H2,(H,19,20)/t11-,13-,15+,16+/m1/s1
• InChIKey: RFQDLTYXNINJON-OYNZBZHQSA-N
• SMILES: B(C(CC1=COC2=CC=CC=C21)NC(=O)C3CC4CCC3O4)(O)O

LMP7-IN-1（Cat No.:I019382） is a compound that can inhibit the activity of immunoproteasome (LMP7). It has potential applications in the research of various diseases including inflammatory and autoimmune diseases, neurodegenerative diseases, proliferative diseases, and cancer. By inhibiting LMP7, LMP7-IN-1 can affect the immune response and the degradation of cellular proteins, which could have therapeutic implications in various diseases.

Reference

[1]. Markus Klein, et al. Boronic acid derivatives. WO2019038250A1.