Lisuride Maleate

• CAT Number: I007677
• CAS Number: 19875-60-6 (maleat); 18016-80-3 (free base).
• Molecular Formula: C24H30N4O5
• Molecular Weight: 454.52
• Purity: ≥95%
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term , or -20°C for long term.

Lisuride maleate is an ergot derivative that acts as an agonist at dopamine D2 receptors, a dopamine agonist. It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors. It displays high affinity for D2, D3 and D4 receptors along with 5-HT1A. Lisuride maleate is also known as an anti-Parkinson/’s agent.

Reference

1:Anticonvulsive effects of the dopamine agonist lisuride maleate after experimental traumatic brain injury. Zweckberger K, Simunovic F, Kiening KL, Unterberg AW, Sakowitz OW.Neurosci Lett. 2010 Feb 12;470(2):150-4. doi: 10.1016/j.neulet.2009.12.075. Epub 2010 Jan 5. PMID: 20056133 2:Symptomatic treatment of premenstrual mastalgia in premenopausal women with lisuride maleate: a double-blind placebo-controlled randomized study. Kaleli S, Aydin Y, Erel CT, Colgar U.Fertil Steril. 2001 Apr;75(4):718-23. PMID: 11287025 3:[Treatment of premenstrual tension syndrome (PMS) with lisuride maleate]. López-Rosales C, Aguilar-Guerrero JA, García-Moreno L.Ginecol Obstet Mex. 1996 Dec;64:556-60. Spanish. PMID: 9019440 4:[Therapeutic effect of lisuride maleate on post-stroke depression]. Hougaku H, Matsumoto M, Hata R, Handa N, Imaizumi M, Sugitani Y, Yoneda S, Etani H, Sueyoshi K, Kusunoki M, et al.Nihon Ronen Igakkai Zasshi. 1994 Jan;31(1):52-9. Japanese. PMID: 8158872 Free Article