For research use only. Not for therapeutic Use.
Linaprazan glurate（Cat No.:I045104）is an investigational potassium-competitive acid blocker (P-CAB) developed for the treatment of acid-related gastrointestinal disorders, including gastroesophageal reflux disease (GERD). It works by reversibly inhibiting the H⁺/K⁺-ATPase enzyme in gastric parietal cells, leading to rapid and sustained suppression of gastric acid secretion. As a prodrug of linaprazan, the glurate form enhances pharmacokinetics and bioavailability. Compared to traditional proton pump inhibitors (PPIs), Linaprazan glurate offers faster onset of action and more consistent acid control. Supplied for research into novel therapies for acid-mediated GI conditions.
| CAS Number | 1228559-81-6 |
| Synonyms | 5-[2-[[8-[(2,6-dimethylphenyl)methylamino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carbonyl]amino]ethoxy]-5-oxopentanoic acid |
| Molecular Formula | C26H32N4O5 |
| Purity | ≥95% |
| IUPAC Name | 5-[2-[[8-[(2,6-dimethylphenyl)methylamino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carbonyl]amino]ethoxy]-5-oxopentanoic acid |
| InChI | InChI=1S/C26H32N4O5/c1-16-7-5-8-17(2)21(16)14-28-22-13-20(15-30-19(4)18(3)29-25(22)30)26(34)27-11-12-35-24(33)10-6-9-23(31)32/h5,7-8,13,15,28H,6,9-12,14H2,1-4H3,(H,27,34)(H,31,32) |
| InChIKey | GPHPBXRKAJSSIC-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=CC=C1)C)CNC2=CC(=CN3C2=NC(=C3C)C)C(=O)NCCOC(=O)CCCC(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
