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LDN-91946

LDN-91946

  • CAT Number: I007636
  • CAS Number: 439946-22-2
  • Molecular Formula: C15H10N2O4S
  • Molecular Weight: 314.347
  • Purity: ≥95%
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LDN-91946 (Cat.No:I007636) is a potent, selective and uncompetitive UCH-L1 inhibitor that targets the enzyme-substrate complex. Inquire LDN-91946 online by filling out the inquiry form, we will get back to you within 24 hours!

Catalog Number I007636
CAS Number 439946-22-2
Molecular Formula

C15H10N2O4S

Purity 95%
Target UCH-L1 inhibitor
Solubility Soluble in DMSO
Storage 0 - 4°C for short term , or -20°C for long term.
IUPAC Name 3-amino-2-benzoyl-6-oxo-4,5,7,7a-tetrahydro-3aH-thieno[2,3-b]pyridine-5-carboxylic acid
InChI InChI=1S/C15H14N2O4S/c16-10-8-6-9(15(20)21)13(19)17-14(8)22-12(10)11(18)7-4-2-1-3-5-7/h1-5,8-9,14H,6,16H2,(H,17,19)(H,20,21)
InChIKey OQYOQOZZWGXGLT-UHFFFAOYSA-N
SMILES C1C2C(NC(=O)C1C(=O)O)SC(=C2N)C(=O)C3=CC=CC=C3
Reference

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1:Coulombe J, Gamage P, Gray MT, Zhang M, Tang MY, Woulfe J, Saffrey MJ, Gray DA. Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system. Front Aging Neurosci. 2014 Jun 19;6:129. doi: 10.3389/fnagi.2014.00129. PubMed PMID: 24994982; PubMed Central PMCID: PMC4063237.

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