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LC3-mHTT-IN-AN2

LC3-mHTT-IN-AN2

  • CAT Number: I017720
  • CAS Number: 7758-73-8
  • Molecular Formula: C₁₅H₁₀O₄
  • Molecular Weight: 254.24
  • Purity: ≥95%
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LC3-mHTT-IN-AN2 (Compound AN2) (Cat.No:I017720) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

Catalog Number I017720
CAS Number 7758-73-8
Molecular Formula

C₁₅H₁₀O₄

Purity 95%
Reference

[1]. Li Z, et al. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds. Nature. 2019 Oct 30.

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