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L-NAME hydrochloride

L-NAME hydrochloride

  • CAT Number: I003841
  • CAS Number: 51298-62-5
  • Molecular Formula: C₇H₁₅N₅O₄.HCl
  • Molecular Weight: 269.69
  • Purity: ≥95%
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L-NAME hydrochloride (Cat.No:I003841) (Nω-Nitro-L-arginine methyl ester hydrochloride) is a potent inhibitor of nitric oxide synthase (NOS), an enzyme responsible for the production of nitric oxide (NO). It is commonly used in research to investigate the role of NO in various physiological and pathological processes. L-NAME hydrochloride helps in understanding the implications of nitric oxide modulation in cardiovascular, neurological, and immune systems.

Catalog Number I003841
CAS Number 51298-62-5
Molecular Formula

C₇H₁₅N₅O₄.HCl

Purity 95%
Target NO synthase
Solubility H2O: ≥ 45 mg/mL
Storage 3 years -20C powder
IC50 4.3 (pIC50, iNOS), 5.7 (pIC50, nNOA) 5.6 (pIC50, eNOS)
InChI InChI=1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1
InChIKey QBNXAGZYLSRPJK-JEDNCBNOSA-N
SMILES COC(=O)C(CCCN=C(N)N[N+](=O)[O-])N.Cl
Reference

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