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KW-8232 free base

KW-8232 free base

  • CAT Number: I020296
  • CAS Number: 170365-25-0
  • Molecular Formula: C₃₆H₃₇ClN₄O₃
  • Molecular Weight: 609.16
  • Purity: ≥95%
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KW-8232 free base (Cat.No:I020296) is a selective and potent antagonist of the neurokinin-2 receptor (NK2 receptor). It blocks the binding of substance P to NK2 receptors, thereby inhibiting the downstream signaling pathways. KW-8232 has been studied for its potential therapeutic applications in various conditions, including gastrointestinal disorders and cancer.

Catalog Number I020296
CAS Number 170365-25-0
Molecular Formula

C₃₆H₃₇ClN₄O₃

Purity 95%
Reference

[1]. Uchii M, et al. Effect of KW-8232, a novel anti-osteoporotic agent, on bone loss in sciatic neurectomized rats. Jpn J Pharmacol. 1998 Oct;78(2):241-3.<br>[2]. Shiwei Wang, et al. A Transferable Deep Learning Approach to Fast Screen Potent Antiviral Drugs against SARS-CoV-2. bioRxiv. 2020.

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