KL1333

• CAT Number: I018055
• CAS Number: 1800405-30-4
• Molecular Formula: C14H12N2O2
• Molecular Weight: 240.26
• Purity: ≥95%
• Synonyms: 2-propan-2-yl-3H-benzo[e]benzimidazole-4,5-dione
• InChI: InChI=1S/C14H12N2O2/c1-7(2)14-15-10-8-5-3-4-6-9(8)12(17)13(18)11(10)16-14/h3-7H,1-2H3,(H,15,16)
• InChIKey: AJFWITSBVLLDCC-UHFFFAOYSA-N
• SMILES: CC(C)C1=NC2=C(N1)C(=O)C(=O)C3=CC=CC=C32

KL1333（Cat No.:I018055）is a novel investigational small molecule targeting mitochondrial disorders by modulating the cellular NAD⁺/NADH balance. It acts as a potent NAD⁺ modulator, enhancing energy metabolism, redox regulation, and mitochondrial biogenesis. Through its mechanism, KL1333 supports ATP production while reducing oxidative stress, offering therapeutic potential in conditions characterized by mitochondrial dysfunction, such as primary mitochondrial diseases. By improving cellular energy homeostasis and protecting against metabolic stress, KL1333 represents a promising approach for treating rare metabolic disorders with high unmet medical need.