• CAT Number: I002975
  • CAS Number: 285986-88-1
  • Molecular Formula: C18H13ClF6N2O3
  • Molecular Weight: 454.75
  • Purity: ≥95%
Inquiry Now

CCG-1423(Cat No.:I002975), is a chemical compound of interest in the field of pharmacology and molecular biology. It is known as a selective inhibitor and is commonly used in laboratory research to target specific signaling pathways or cellular processes. Detailed studies may vary, but CCG-1423 is typically explored for its potential in modulating specific molecular targets within cells.

Catalog Number I002975
CAS Number 285986-88-1


Molecular Formula


Purity 95%
Target Rho
Solubility DMSO: ≥ 26 mg/mL
Storage Store at -20°C
IC50 1.5 uM
IUPAC Name N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide
InChI InChI=1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29)

</br>1:Stereospecific Inhibitory Effects of CCG-1423 on the Cellular Events Mediated by Myocardin-Related Transcription Factor A. Watanabe B, Minami S, Ishida H, Yoshioka R, Nakagawa Y, Morita T, Hayashi K.PLoS One. 2015 Aug 21;10(8):e0136242. doi: 10.1371/journal.pone.0136242. eCollection 2015. PMID: 26295164 Free PMC Article</br>2:RPEL proteins are the molecular targets for CCG-1423, an inhibitor of Rho signaling. Hayashi K, Watanabe B, Nakagawa Y, Minami S, Morita T.PLoS One. 2014 Feb 18;9(2):e89016. doi: 10.1371/journal.pone.0089016. eCollection 2014. PMID: 24558465 Free PMC Article</br>3:Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway. Bell JL, Haak AJ, Wade SM, Sun Y, Neubig RR, Larsen SD.Beilstein J Org Chem. 2013 May 21;9:966-73. doi: 10.3762/bjoc.9.111. Print 2013. PMID: 23766813 Free PMC Article</br>4:Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423. Evelyn CR, Bell JL, Ryu JG, Wade SM, Kocab A, Harzdorf NL, Showalter HD, Neubig RR, Larsen SD.Bioorg Med Chem Lett. 2010 Jan 15;20(2):665-72. doi: 10.1016/j.bmcl.2009.11.056. Epub 2009 Nov 18. PMID: 19963382 Free PMC Article</br>5:CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling. Evelyn CR, Wade SM, Wang Q, Wu M, Iñiguez-Lluhí JA, Merajver SD, Neubig RR.Mol Cancer Ther. 2007 Aug;6(8):2249-60. PMID: 17699722 Free Article

Request a Quote

Contact Us at MuseChem

We are committed to providing you with reliable, cost-effective solutions for your chemical needs, while ensuring your safety and comfort. Our team of experts is always available to answer your questions and help you navigate the complexities of the chemical industry.

Whether you're looking for a specific product or need help with a custom synthesis project, we're here to help you discover a new world of chemical possibilities. Contact us today to learn more about how we can assist you with all of your chemical needs.

Our goal is to make the process of ordering chemicals as seamless and hassle-free as possible. Let us know how we can assist you, and we'll get back to you as soon as possible. We look forward to hearing from you!