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KIN1148

KIN1148

  • CAT Number: I013398
  • CAS Number: 1428729-56-9
  • Molecular Formula: C₁₉H₁₁N₃OS₂
  • Molecular Weight: 361.44
  • Purity: ≥95%
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KIN1148 (Cat No.:I013398) is an agonist of interferonregulatoryfactor3 (IRF3), which induces dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. KIN1148 is an influenza vaccine adjuvant that enhances the efficacy of influenza vaccines.

Catalog Number I013398
CAS Number 1428729-56-9
Molecular Formula

C₁₉H₁₁N₃OS₂

Purity 95%
Target HSP
Solubility DMSO: ≥100 mg/mL
Storage Store at -20°C
IUPAC Name N-([1,3]thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide
InChI InChI=1S/C19H11N3OS2/c23-18(13-6-5-11-3-1-2-4-12(11)9-13)22-19-21-14-7-8-15-16(17(14)25-19)20-10-24-15/h1-10H,(H,21,22,23)
InChIKey YAISOECYKYATLL-UHFFFAOYSA-N
SMILES C1=CC=C2C=C(C=CC2=C1)C(=O)NC3=NC4=C(S3)C5=C(C=C4)SC=N5
Reference

[1]. Probst P, et al. A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response. Vaccine. 2017 Apr 4;35(15):1964-1971.

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