Kif15-IN-1

  • CAT Number: I004527
  • CAS Number: 672926-32-8
  • Molecular Formula: C20H22N4O5S
  • Molecular Weight: 430.48
  • Purity: ≥95%
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<p style=/line-height:25px/>Kif15-IN-1 is a potent Kif15 kinesin inhibitor; inhibits cellular proliferation in tumor cell lines.<br>IC50 value:<br>Target: Kif15<br>Mitotic kinesins are attractive targets for the discovery and development of novel antimitotic chemotherapeutics. Accordingly, it is an object of the present invention to provide methods, compounds, and compositions useful in the inhibition of HsKif15, a mitotic kinesin.</p>

Catalog Number I004527
CAS Number 672926-32-8
Synonyms

(S,Z)-N-(5-(ethoxycarbonyl)-4-methylthiazol-2-yl)-2-(2-hydroxy-4-oxoquinazolin-3(4H)-yl)-3-methylbutanimidic acid

Molecular Formula

C20H22N4O5S

Purity 95%
Target Kinesin
Solubility 10 mM in DMSO
Storage Store at +4C
Reference

<p style=/line-height:25px/>
<br>[1]. Preparation of quinazolinediones as Kif15 kinesin inhibitors for treating cellular proliferative disorders. Pat. Appl. Publ. (2004), US 20040053948 A1 20040318.

</p>

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