(-)-Ketoconazole

  • CAT Number: R036160
  • CAS Number: 142128-57-2
  • Molecular Formula: C26H28Cl2N4O4
  • Molecular Weight: 531.43
  • Purity: ≥95%
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(-)-Ketoconazole(Cat No.:R036160), also known as (-)-R 41400, is one of the enantiomers of ketoconazole. Ketoconazole itself is a racemic mixture consisting of two enantiomers: lev ketoconazole and dexketoconazole. Enantiomers are mirror images of each other and possess different biological activities. (-)-Ketoconazole specifically refers to the stereochemistry of one enantiomer within the ketoconazole molecule. The enantiomeric composition of ketoconazole can have implications for its pharmacological properties, metabolism, and potential therapeutic applications.

Catalog Number R036160
CAS Number 142128-57-2
Molecular Formula

C26H28Cl2N4O4

Purity 95%
Storage RT
IUPAC Name 1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1
InChIKey XMAYWYJOQHXEEK-ZEQKJWHPSA-N
SMILES CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl

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