KDM4D-IN-1

  • CAT Number: I013216
  • CAS Number: 2098902-68-0
  • Molecular Formula: C₁₁H₇N₅O
  • Molecular Weight: 225.21
  • Purity: ≥95%
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KDM4D-IN-1 is a new histone lysine demethylase 4D (KDM4D) inhibitor with an IC50 value of 0.41±0.03 μM.

Catalog Number I013216
CAS Number 2098902-68-0
Molecular Formula

C₁₁H₇N₅O

Purity 95%
Target Histone Demethylase
Solubility DMSO: 6 mg/mL (Need ultrasonic)
InChI InChI=1S/C11H7N5O/c1-6-8(5-12)10-14-11(17)7-3-2-4-13-9(7)16(10)15-6/h2-4,15H,1H3
InChIKey ACTIHECDWUUJPX-UHFFFAOYSA-N
SMILES CC1=C(C2=NC(=O)C3=C(N2N1)N=CC=C3)C#N
Reference

[1]. Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett. 2017 Jul 15;27(14):3201-3204.

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