KALIOTOXIN (1-37)

• CAT Number: P000019
• Molecular Formula: C19H28F6NO5PS
• Purity: ≥95%
• Solubility: In water and saline
• Storage: Stable in freeze-dried state. In solution, keep at -20 °C.

KALIOTOXIN (1-37) is a blocker of Ca2+-activated K+ channels of high conductance and some voltage-dependent K+ channels.
In human and murin β-lymphocytes, where both K+ channels subtypes are present, Kaliotoxin (1-37) is a selective voltage-dependent K+ channels blocker.


37-amino acid peptide with 3 disulfide bridges<!—->, synthetic, originally from Androctonus mauretanicus mauretanicus scorpion venom.

Kaliotoxin (1-37) presents the same biological activity as Kaliotoxin (KTX).
Neurons:

Reference

– Crest et al., /Kaliotoxin, a novel peptidyl inhibitor of neuronal BK-type Ca2+-activated K+ channels characterized from Androctonus mauretanicus mauretanicus venom./ J. Biol. Chem. (1992). 267(3):1640-1647