K-115 free base - CAS 223645-67-8
K-115 free base(CAT: I002718), also known as K-115 hydrochloride, is a highly selective and potent inhibitor of Rho-kinase. It belongs to the class of isoquinolinesulfonamide compounds and has an IC50 value of 31 nM, indicating its strong inhibitory activity against Rho-kinase. Rho-kinase is an enzyme involved in the regulation of various cellular processes, including smooth muscle contraction, cell motility, and cytoskeletal organization. By inhibiting Rho-kinase, K-115 free base has the potential to modulate these processes, making it a valuable tool in research and potentially for therapeutic applications.
Catalog Number: I002718
CAS Number: 223645-67-8
PubChem Substance ID:355038117
Molecular Formula: C15H18FN3O2S
Molecular Weight:323.39
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Property
| Molecular Formula: | C15H18FN3O2S |
|---|---|
| Molecular Weight | 323.39 |
| Target: | ROCK inhibitor |
| Solubility | 10 mM in DMSO |
| Purity | ≥95% |
| Storage | Store at -20°C |
| IC50 | 31 nM [1] |