K-115 free base - CAS 223645-67-8

K-115 free base(CAT: I002718), also known as K-115 hydrochloride, is a highly selective and potent inhibitor of Rho-kinase. It belongs to the class of isoquinolinesulfonamide compounds and has an IC50 value of 31 nM, indicating its strong inhibitory activity against Rho-kinase. Rho-kinase is an enzyme involved in the regulation of various cellular processes, including smooth muscle contraction, cell motility, and cytoskeletal organization. By inhibiting Rho-kinase, K-115 free base has the potential to modulate these processes, making it a valuable tool in research and potentially for therapeutic applications.

Catalog Number: I002718

CAS Number: 223645-67-8

PubChem Substance ID:355038117

Molecular Formula: C15H18FN3O2S

Molecular Weight:323.39

Purity: ≥95%

* For research use only. Not for human or veterinary use.


Molecular Formula: C15H18FN3O2S
Molecular Weight323.39
Target:ROCK inhibitor
Solubility10 mM in DMSO
StorageStore at -20°C
IC5031 nM [1]