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JWH 182

JWH 182

  • CAT Number: R048051
  • CAS Number: 824960-02-3
  • Molecular Formula: C27H29NO
  • Molecular Weight: 383.535
  • Purity: ≥95%
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JWH 182 is a potent synthetic cannabinoid (CB), activating the central CB<sub>1</sub> receptor with a K<sub>i</sub> value of 0.65 nM and the peripheral CB<sub>2</sub> receptor with a K<sub>i</sub> value of 1.1 nM. Its effects in cells and animals are unknown.

Catalog Number R048051
CAS Number 824960-02-3
Synonyms

(1-pentyl-1H-indol-3-yl)(4-propyl-1-naphthalenyl)-methanone

Molecular Formula

C27H29NO

Purity 95%
IUPAC Name (1-pentylindol-3-yl)-(4-propylnaphthalen-1-yl)methanone
InChI InChI=1S/C27H29NO/c1-3-5-10-18-28-19-25(23-14-8-9-15-26(23)28)27(29)24-17-16-20(11-4-2)21-12-6-7-13-22(21)24/h6-9,12-17,19H,3-5,10-11,18H2,1-2H3
InChIKey AKGUMDFQXWZHHS-UHFFFAOYSA-N
SMILES CCCCCN1C=C(C2=CC=CC=C21)C(=O)C3=CC=C(C4=CC=CC=C43)CCC
Reference

1.Huffman, J.W.,Zengin, G.,Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists.

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