For research use only. Not for therapeutic Use.
JAK2-IN-6（Cat No.:I044655）is a selective small-molecule inhibitor targeting Janus kinase 2 (JAK2), a critical component of the JAK/STAT signaling pathway involved in hematopoiesis, inflammation, and oncogenesis. By inhibiting JAK2 activity, JAK2-IN-6 blocks downstream phosphorylation of STAT proteins, effectively modulating aberrant cytokine signaling. It is particularly relevant in studying myeloproliferative disorders, autoimmune diseases, and JAK2-driven malignancies. With high potency and selectivity, JAK2-IN-6 serves as a valuable tool for dissecting JAK2-specific biological effects and evaluating potential therapeutic interventions in preclinical disease models involving dysregulated JAK/STAT signaling.
| CAS Number | 353512-04-6 |
| Synonyms | (4-amino-2-anilino-1,3-thiazol-5-yl)-(5-chlorothiophen-2-yl)methanone |
| Molecular Formula | C14H10ClN3OS2 |
| Purity | ≥95% |
| IUPAC Name | (4-amino-2-anilino-1,3-thiazol-5-yl)-(5-chlorothiophen-2-yl)methanone |
| InChI | InChI=1S/C14H10ClN3OS2/c15-10-7-6-9(20-10)11(19)12-13(16)18-14(21-12)17-8-4-2-1-3-5-8/h1-7H,16H2,(H,17,18) |
| InChIKey | OFSYMZBCAABWIK-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)NC2=NC(=C(S2)C(=O)C3=CC=C(S3)Cl)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
