Isocurcumenol

• CAT Number: I017071
• CAS Number: 24063-71-6
• Molecular Formula: C₁₅H₂₂O₂
• Molecular Weight: 234.33
• Purity: ≥95%
• Storage: -20°C, protect from light
• IUPAC Name: (1S,2S,5S,8R)-2-methyl-6-methylidene-9-propan-2-ylidene-11-oxatricyclo[6.2.1.01,5]undecan-8-ol
• InChI: InChI=1S/C15H22O2/c1-9(2)13-8-14-11(4)5-6-12(14)10(3)7-15(13,16)17-14/h11-12,16H,3,5-8H2,1-2,4H3/t11-,12-,14-,15+/m0/s1
• InChIKey: DEBDFZGNZTYPMF-NZBPQXDJSA-N
• SMILES: CC1CCC2C13CC(=C(C)C)C(O3)(CC2=C)O

Isocurcumenol (Cat No.: I017071) has a significant anti-inflammatory effect and can significantly inhibit the production of NO in macrophages stimulated by lipopolysaccharide. Isocurcumenol belongs to the guaiac ane-type sesquiterpene, which is a five-membered ring and a seven-membered ring in parallel structure. Isocurcumenol has the effects of promoting qi and breaking blood, eliminating stagnation, and relieving pain. Clinically more commonly used drugs for promoting blood circulation and removing blood stasis.

Reference

[1]. Lakshmi S, et al. Antitumour Effects of Isocurcumenol Isolated from Curcuma zedoaria Rhizomes on Human and Murine Cancer Cells. Int J Med Chem. 2011;2011:253962.[2]. Resmi Mustarichiei, et al. In silico study of curcumol, curcumenol, isocurcumenol, and β-sitosterol as potential inhibitors of estrogen receptor alpha of breast cancer. Basic Medical Research. 2014