For research use only. Not for therapeutic Use.
IPN60090（Cat No.:I015449）is an experimental small-molecule inhibitor targeting the fibroblast growth factor receptor (FGFR) family, developed for oncology research. By selectively blocking FGFR signaling pathways, it interferes with tumor growth, angiogenesis, and cell survival driven by FGFR alterations. This compound is being evaluated in cancers with FGFR genetic abnormalities, such as urothelial carcinoma, cholangiocarcinoma, and certain solid tumors. Its potency and oral bioavailability make it a promising therapeutic candidate in precision medicine. IPN60090 serves as a valuable tool for studying FGFR-driven oncogenesis and targeted cancer therapies.
| CAS Number | 1853164-83-6 |
| Synonyms | 1-[(2R)-4-[6-[[2-[4-(3,3-difluorocyclobutyl)oxy-6-methylpyridin-2-yl]acetyl]amino]pyridazin-3-yl]-2-fluorobutyl]-N-methyltriazole-4-carboxamide |
| Molecular Formula | C24H27F3N8O3 |
| Purity | ≥95% |
| IUPAC Name | 1-[(2R)-4-[6-[[2-[4-(3,3-difluorocyclobutyl)oxy-6-methylpyridin-2-yl]acetyl]amino]pyridazin-3-yl]-2-fluorobutyl]-N-methyltriazole-4-carboxamide |
| InChI | InChI=1S/C24H27F3N8O3/c1-14-7-18(38-19-10-24(26,27)11-19)8-17(29-14)9-22(36)30-21-6-5-16(31-33-21)4-3-15(25)12-35-13-20(32-34-35)23(37)28-2/h5-8,13,15,19H,3-4,9-12H2,1-2H3,(H,28,37)(H,30,33,36)/t15-/m1/s1 |
| InChIKey | GEHZIZWHNLQFAS-OAHLLOKOSA-N |
| SMILES | CC1=CC(=CC(=N1)CC(=O)NC2=NN=C(C=C2)CC[C@H](CN3C=C(N=N3)C(=O)NC)F)OC4CC(C4)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
