Indican

• CAT Number: I014406
• CAS Number: 487-60-5
• Molecular Formula: C14H17NO6
• Molecular Weight: 295.29
• Purity: ≥95%
• Synonyms: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(1H-indol-3-yloxy)oxane-3,4,5-triol
• InChI: InChI=1S/C14H17NO6/c16-6-10-11(17)12(18)13(19)14(21-10)20-9-5-15-8-4-2-1-3-7(8)9/h1-5,10-19H,6H2/t10-,11-,12+,13-,14-/m1/s1
• InChIKey: XVARCVCWNFACQC-RKQHYHRCSA-N
• SMILES: C1=CC=C2C(=C1)C(=CN2)OC3C(C(C(C(O3)CO)O)O)O

Indican (Cat No.: I014406) is a naturally occurring glycoside formed when indoxyl binds glucose. It is found in certain plants, such as Indigofera, where it serves as a precursor for the blue dye indigo upon enzymatic hydrolysis and oxidation. In human physiology, urinary indican arises from gut microbial metabolism of tryptophan, with elevated levels indicating intestinal dysbiosis or malabsorption syndromes. Thus, indican is important both as a biochemical marker of gastrointestinal health and as a plant-derived compound with industrial relevance.

Reference

[1]. Shiuan-Pey Lin, et al. Transporter-mediated interaction of indican and methotrexate in rats. J Food Drug Anal. 2018 Apr;26(2S):S133-S140.
[Content Brief]

[2]. Yu-Chi Hou, et al. Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-beta-D-glucoside (indican) in rats. Toxicon. 2008 Sep 1;52(3):440-4.
[Content Brief]