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Impurity C of Alfacalcidol

Impurity C of Alfacalcidol

  • CAT Number: I004978
  • CAS Number: 82266-85-1
  • Molecular Formula: C35H49N3O4
  • Molecular Weight: 575.78
  • Purity: ≥95%
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<p style=/line-height:25px/>Impurity of Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.<br>IC50 value:<br>Target: VDR activator<br>Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo.</p>

Catalog Number I004978
CAS Number 82266-85-1
Molecular Formula

C35H49N3O4

Purity 95%
Target VD/VDR
Solubility 10 mM in DMSO
Storage Store at -20°C
Reference

<p style=/line-height:25px/>
<br>[1]. Shiraishi et al (2000) Alfacalcidol inhibits bone resorption and stmulates formation in an ovariectomized rat model of osteoporosis: Distinct actions from estrogen. Journal of Bone and Mineral Research. 15 770.
<br>[2]. Ringe JD, Schacht E. et al. Prevention and therapy of osteoporosis: the roles of plain vitamin D and alfacalcidol. Rheumatol Int. 2004 Jul;24(4):189-97.
<br>[3]. Ivarsen P, Povlsen JV, Christensen KL.Effect of alfacalcidol on cardiac function in patients with chronic kidney disease stage 4 and secondary hyperparathyroidism: A pilot study.Scand J Urol Nephrol. 2012 Jun 25.
<br>[4]. Rianthavorn P, Pisutikul K, Deekajorndech T, Tepmongkol S, Suphapeetiporn K.Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone.J Pediatr Endocrinol Metab. 2012;25(3-4):307-12.
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