For research use only. Not for therapeutic Use.
Imlunestrant（Cat No.:I045106）is an investigational oral selective estrogen receptor degrader (SERD) developed for the treatment of estrogen receptor-positive (ER+) breast cancer. It binds to the estrogen receptor (ER), induces its degradation, and inhibits estrogen-driven transcriptional activity, thereby blocking tumor growth. Imlunestrant is designed to overcome resistance to first-generation endocrine therapies, such as tamoxifen and aromatase inhibitors. Its oral bioavailability and targeted mechanism offer a convenient and effective alternative to injectable SERDs. Supplied for research into hormone receptor signaling, endocrine resistance, and advanced breast cancer therapeutics.
| CAS Number | 2408840-26-4 |
| Synonyms | (5R)-5-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenyl]-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol |
| Molecular Formula | C29H24F4N2O3 |
| Purity | ≥95% |
| IUPAC Name | (5R)-5-[4-[2-[3-(fluoromethyl)azetidin-1-yl]ethoxy]phenyl]-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol |
| InChI | InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2/t28-/m1/s1 |
| InChIKey | UVBQMXOKKDCBJN-MUUNZHRXSA-N |
| SMILES | C1C(CN1CCOC2=CC=C(C=C2)[C@@H]3C4=C5C=CC(=CC5=NC=C4C6=C(O3)C=C(C=C6)C(F)(F)F)O)CF |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
