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Imiloxan

Imiloxan

  • CAT Number: I007284
  • CAS Number: 81167-16-0
  • Molecular Formula: C14H16N2O2
  • Molecular Weight: 244.294
  • Purity: ≥95%
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Imiloxan, also known as RS-21361, is an α2 adrenergic receptor antagonist potentially for the treatment of major depressive disorder.

Catalog Number I007284
CAS Number 81167-16-0
Molecular Formula

C14H16N2O2

Purity 95%
Target α2 adrenergic receptor antagonist
Solubility Soluble in DMSO
Storage 0 - 4°C for short term , or -20°C for long term.
Reference

</br>1:Application of modern drug metabolism structure determination tools and assays to the in vitro metabolism of imiloxan. Fitch WL, Chen Y, Liu L, Paehler A, Young M.Drug Metab Lett. 2010 Apr;4(2):77-87. PMID: 20446913 </br>2:The effect of intrathecally administered imiloxan and WB4101: possible role of alpha 2-adrenoceptor subtypes in the spinal cord. Takano Y, Takano M, Yaksh TL.Eur J Pharmacol. 1992 Sep 4;219(3):465-8. PMID: 1358645 </br>3:The metabolism of imiloxan hydrochloride in healthy male volunteers. Rush WR, Hall DJ, Graham DJ, Selby IA.Xenobiotica. 1992 Feb;22(2):237-46. PMID: 1352928 </br>4:Assessment of imiloxan as a selective alpha 2B-adrenoceptor antagonist. Michel AD, Loury DN, Whiting RL.Br J Pharmacol. 1990 Mar;99(3):560-4. PMID: 1970500 Free PMC Article

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