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Imidafenacin

Imidafenacin

  • CAT Number: I002223
  • CAS Number: 170105-16-5
  • Molecular Formula: C20H21N3O
  • Molecular Weight: 319.4
  • Purity: ≥95%
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Imidafenacin (Cat. No: I002223) is a new type of diphenylbutyramide anticholinergic drug. It selectively acts on M3 and M1 muscarinic subtype receptors and has high bladder selectivity. It can be used to treat urinary frequency, urinary urgency and urinary incontinence caused by overactive bladder.

Catalog Number I002223
CAS Number 170105-16-5
Molecular Formula

C20H21N3O

Purity 95%
Solubility DMSO：≥ 7.8 mg/mL
Storage Store at -20°C
IC50 0.3 nM(M3) [1]
Reference

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<br>[1]. Miyachi H, et al. Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents. Bioorg Med Chem. 1999 Jun;7(6):1151-61.
<br>[2]. Yamazaki T, et al. Imidafenacin has no influence on learning in nucleus basalis of Meynert-lesioned rats. Naunyn Schmiedebergs Arch Pharmacol. 2013 Dec;386(12):1095-102.
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