Imatinib metabolite N-Desmethyl Imatinib

• CAT Number: I003468
• CAS Number: 404844-02-6
• Molecular Formula: C28H29N7O
• Molecular Weight: 479.58
• Purity: ≥95%
• Solubility: DMSO:30mg/mL
• Storage: 3 years -20℃ powder
• IUPAC Name: N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]-4-(piperazin-1-ylmethyl)benzamide
• InChI: InChI=1S/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34)
• InChIKey: BQQYXPHRXIZMDM-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCNCC3)NC4=NC=CC(=N4)C5=CN=CC=C5

Imatinib metabolite N-Desmethyl Imatinib (Cat.No:I003468) is an active metabolite of Imatinib, a tyrosine kinase inhibitor used in the treatment of certain cancers. N-Desmethyl Imatinib retains the ability to inhibit certain kinases, including Bcr-Abl and c-Kit. It contributes to the overall pharmacological effects of Imatinib and is involved in its therapeutic activity.