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Hydroxyzine Dihydrochloride

Hydroxyzine Dihydrochloride

  • CAT Number: A000420
  • CAS Number: 2192-20-3
  • Molecular Formula: C21H29Cl3N2O2
  • Molecular Weight: 447.83
  • Purity: ≥95%
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Hydroxazine hydrochloride (Cat No.:A000420) is the first generation antihistamine with low toxicity. It has the effects of relaxing striated muscle, antihistamine and choline, inhibiting central nervous system, stabilizing, antihistamine, antiemetic and antispasmodic. In addition, it can reduce the pressure of adrenaline and quinidine like antiarrhythmic effect.

Catalog Number A000420
CAS Number 2192-20-3
Molecular Formula

C21H29Cl3N2O2

Purity 95%
Target Histamine Receptor
Solubility >17.2mg/mL in DMSO
Storage -20°C
InChI 1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H
InChIKey ANOMHKZSQFYSBR-UHFFFAOYSA-N
SMILES C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl
Reference

1: Mumtaz A, Hussain S, Yasir M. Green approach towards the determination of
hydroxyzine dihydrochloride in pure and pharmaceutical dosage forms. Pak J Pharm
Sci. 2014 Sep;27(5):1157-62. PubMed PMID: 25176372.

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2: Sawicki B, Janik B. [Determination of hydroxyzine dihydrochloride (atarax) by
means of sodium tetraphenylborate]. Acta Pol Pharm. 1966;23(6):573-5. Polish.
PubMed PMID: 5960089.

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