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Hydroxy-PEG6-Boc

Hydroxy-PEG6-Boc

  • CAT Number: I016590
  • CAS Number: 361189-64-2
  • Molecular Formula: C₁₉H₃₈O₉
  • Molecular Weight: 410.5
  • Purity: ≥95%
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Hydroxy-PEG6-Boc (CAT: I016590) represents a versatile PEG-based PROTAC linker, strategically engineered for use in the synthesis of Proteolysis-Targeting Chimeras (PROTACs). With its hydroxy-terminated polyethylene glycol (PEG) backbone and Boc (tert-butyloxycarbonyl) protecting group, this linker offers a tailored platform for the construction of novel molecular entities. Integrating this linker into PROTAC design, it enables precise conjugation of target-specific ligands and E3 ligase-recruiting moieties, facilitating the targeted degradation of disease-associated proteins.

Catalog Number I016590
CAS Number 361189-64-2
Molecular Formula

C₁₉H₃₈O₉

Purity 95%
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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