Hydroxy Dabrafenib

• CAT Number: C000221
• CAS Number: 1195767-77-1
• Molecular Formula: C₂₃H₂₀F₃N₅O₃S₂
• Molecular Weight: 535.56
• Purity: ≥95%
• Synonyms: N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(2-hydroxy-1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Storage: 4°C, Inert atmosphere

Hydroxy Dabrafenib (CAT: C000221) is a derivative of Dabrafenib, a medication used in the treatment of certain types of cancer, particularly melanoma with specific genetic mutations. Hydroxy Dabrafenib may be a metabolite or an intermediate in the metabolism or synthesis of Dabrafenib.

Reference

Vikingsson, S., et al.: Analy. and Bioanaly. Chem., 409(15), 3749-3756 (2017); Bershas, D. A., et al.: Drug Metabol. & Dispos., 41(12), 2215-2224 (2013)