Hydrocortisone hemisuccinate

• CAT Number: I011928
• CAS Number: 2203-97-6
• Molecular Formula: C25H34O8
• Molecular Weight: 462.53
• Purity: ≥95%
• Synonyms: 4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
• InChI: InChI=1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1
• InChIKey: VWQWXZAWFPZJDA-CGVGKPPMSA-N
• SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)COC(=O)CCC(=O)O)O)C)O

Hydrocortisone hemisuccinate（Cat No.:I011928）is a water-soluble corticosteroid used for rapid systemic administration in emergency and acute care settings. As a hemisuccinate ester of hydrocortisone, it offers enhanced solubility for intravenous or intramuscular injection. It exerts anti-inflammatory and immunosuppressive effects by modulating gene expression and inhibiting pro-inflammatory cytokines. Commonly used in adrenal insufficiency, severe allergic reactions, shock, and autoimmune disorders, it provides quick relief from inflammation and stress-related responses. Hydrocortisone hemisuccinate is favored for its fast onset and is essential in managing acute adrenal crises and critical inflammatory conditions.