HT-2 Toxin

• CAT Number: R058413
• CAS Number: 26934-87-2
• Molecular Formula: C22H32O8
• Molecular Weight: 424.48
• Purity: ≥95%
• Synonyms: [(1S,2R,4S,7R,9R,10R,11S,12S)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2′-oxirane]-4-yl] 3-methylbutanoate
• IUPAC Name: [(1S,2R,4S,7R,9R,10R,11S,12S)-2-(acetyloxymethyl)-10,11-dihydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-yl] 3-methylbutanoate
• InChI: InChI=1S/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22-/m0/s1
• InChIKey: PNKLMTPXERFKEN-MLXHEQMXSA-N
• SMILES: CC1=C[C@@H]2[C@](C[C@@H]1OC(=O)CC(C)C)([C@]3([C@@H]([C@H]([C@H]([C@@]34CO4)O2)O)O)C)COC(=O)C

HT-2 toxin（Cat No.:R058413）is a trichothecene mycotoxin produced by Fusarium species that frequently contaminate cereals such as oats, wheat, and barley. It is a highly toxic metabolite of T-2 toxin, known for inhibiting protein synthesis by binding to ribosomes, leading to immunosuppression, cytotoxicity, and apoptosis. Exposure to HT-2 toxin is linked to feed refusal, growth impairment, and reproductive toxicity in animals, while raising concerns for human health. Due to its potency, it is studied in toxicology, food safety, and agricultural sciences to understand risks and develop mitigation strategies.