Histone H2A (1-20)

• CAT Number: I044274
• Molecular Formula: C83H155N37O26
• Molecular Weight: 2087.35
• Purity: ≥95%
• IUPAC Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[2-[[2-[[(2S)-5-amino-2-[[(2S)-6-amino-2-[[2-[[(2S)-2-[[2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]acetyl]amino]hexanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]hexanoyl]amino]propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-carbamimidamidopentanoic acid
• InChI: InChI=1S/C83H155N37O26/c1-42(106-70(136)48(17-5-9-27-84)110-60(127)36-102-59(126)35-104-69(135)54(25-26-58(89)125)115-73(139)49(18-6-10-28-85)111-62(129)38-105-68(134)47(21-13-31-98-80(90)91)109-61(128)37-103-67(133)46(88)39-121)66(132)114-52(22-14-32-99-81(92)93)72(138)108-43(2)64(130)112-50(19-7-11-29-86)71(137)107-44(3)65(131)113-51(20-8-12-30-87)75(141)120-63(45(4)124)78(144)116-53(23-15-33-100-82(94)95)74(140)118-57(41-123)77(143)119-56(40-122)76(142)117-55(79(145)146)24-16-34-101-83(96)97/h42-57,63,121-124H,5-41,84-88H2,1-4H3,(H2,89,125)(H,102,126)(H,103,133)(H,104,135)(H,105,134)(H,106,136)(H,107,137)(H,108,138)(H,109,128)(H,110,127)(H,111,129)(H,112,130)(H,113,131)(H,114,132)(H,115,139)(H,116,144)(H,117,142)(H,118,140)(H,119,143)(H,120,141)(H,145,146)(H4,90,91,98)(H4,92,93,99)(H4,94,95,100)(H4,96,97,101)/t42-,43-,44-,45+,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,63-/m0/s1
• InChIKey: CCAFITMPUHZBFY-YKPYOGORSA-N
• SMILES: C[C@H]([C@@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)N)O

Histone H2A (1–20)（Cat No.:I044274）is a synthetic peptide corresponding to the first 20 amino acids of the N-terminal tail of histone H2A, a core component of the nucleosome. This region is rich in lysine and serine residues, making it a target for various post-translational modifications such as acetylation, phosphorylation, and methylation. These modifications regulate chromatin structure and gene expression. The H2A (1–20) peptide is widely used in epigenetics research to study protein interactions, antibody specificity, and histone-modifying enzymes. It serves as a model substrate in assays exploring chromatin dynamics and transcriptional regulation.