Histone H1-derived Peptide

For research use only. Not for therapeutic Use.

  • CAT Number: I044284
  • CAS Number: 889112-06-5
  • Molecular Formula: C56H101N17O15
  • Molecular Weight: 1252.51
  • Purity: ≥95%
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Histone H1-derived peptide(Cat No.:I044284)is a synthetic fragment originating from histone H1, a linker histone involved in higher-order chromatin structure and DNA packaging. Unlike core histones (H2A, H2B, H3, H4), H1 binds to the nucleosome and the entry/exit sites of DNA, influencing gene accessibility and regulation. Peptides derived from histone H1 are widely used to study chromatin remodeling, epigenetic regulation, and histone-protein interactions. They may also exhibit antimicrobial or immunomodulatory properties due to their cationic and amphipathic nature, making them relevant in cancer research, drug delivery, and innate immunity investigations.


CAS Number 889112-06-5
Molecular Formula C56H101N17O15
Purity ≥95%
IUPAC Name (2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-1-[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]hexanoyl]amino]propanoyl]amino]hexanoyl]amino]hexanoyl]amino]-4-methylpentanoic acid
InChI InChI=1S/C56H101N17O15/c1-32(2)28-40(56(87)88)70-52(83)38(18-8-12-24-59)68-50(81)37(17-7-11-23-58)66-47(78)33(3)64-49(80)36(16-6-10-22-57)67-51(82)39(19-9-13-25-60)69-54(85)42-21-15-27-73(42)55(86)46(35(5)74)71-48(79)34(4)65-53(84)41-20-14-26-72(41)45(77)31-63-44(76)30-62-43(75)29-61/h32-42,46,74H,6-31,57-61H2,1-5H3,(H,62,75)(H,63,76)(H,64,80)(H,65,84)(H,66,78)(H,67,82)(H,68,81)(H,69,85)(H,70,83)(H,71,79)(H,87,88)/t33-,34-,35+,36-,37-,38-,39-,40-,41-,42-,46-/m0/s1
InChIKey MLODEUSVVAOABW-PNNPTOSWSA-N
SMILES C[C@H]([C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)CNC(=O)CN)O
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