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Hexane-1,6-diyldiphosphonic acid

Hexane-1,6-diyldiphosphonic acid

  • CAT Number: I016039
  • CAS Number: 4721-22-6
  • Molecular Formula: C₆H₁₆O₆P₂
  • Molecular Weight: 246.14
  • Purity: ≥95%
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Hexane-1,6-diyldiphosphonic acid(CAT: I016039) is a valuable alkyl chain-based linker commonly employed in the synthesis of PROTACs (PROteolysis TArgeting Chimeras). This molecule serves as a versatile bridge, enabling the precise connection of two different moieties in a PROTAC, such as a target-binding ligand and an E3 ligase ligand. The hexane-based linker provides the appropriate length and flexibility for maintaining optimal interactions between these components.

Catalog Number I016039
CAS Number 4721-22-6
Molecular Formula

C₆H₁₆O₆P₂

Purity 95%
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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