Guanfacine

• CAT Number: I003012
• CAS Number: 29110-47-2
• Molecular Formula: C9H9Cl2N3O
• Molecular Weight: 246.09
• Purity: ≥95%
• Target: Adrenergic Receptor
• Solubility: water：1.89 mg/ml ；
• Storage: Store at -20C

Guanfacine（Cat No.:I003012） is a medication that acts as a selective agonist of the α2A adrenergic receptor. By binding and activating these receptors, guanfacine exerts its therapeutic effects. It is primarily used in the treatment of attention deficit hyperactivity disorder (ADHD) and hypertension. Guanfacine’s activation of α2A receptors leads to decreased sympathetic outflow, resulting in a reduction of ADHD symptoms and a lowering of blood pressure. It’s selective targeting of α2A receptors allows for specific modulation of adrenergic signaling pathways involved in these conditions.

Reference

[1]. Kolar, D., et al., Treatment of adults with attention-deficit/hyperactivity disorder. Neuropsychiatr Dis Treat, 2008. 4(2): p. 389-403.

[2]. Zwieten, P.v., M. Thoolen, and P. Timmermans, The pharmacology of centrally acting antihypertensive drugs. British journal of clinical pharmacology, 1983. 15(Supplement s4): p. 455S-462S.