Guaifenesin

• CAT Number: A000410
• CAS Number: 93-14-1
• Molecular Formula: C10H14O4
• Molecular Weight: 198.2
• Purity: ≥95%
• Storage: -20°C
• InChI: 1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3
• InChIKey: HSRJKNPTNIJEKV-UHFFFAOYSA-N
• SMILES: COC1=CC=CC=C1OCC(CO)O

Guaifenesin is an expectorant reported to have muscle relaxant and sedative activity. It is used in many cough preparations.

Reference

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3: Collaku A, Yue Y, Reed K. Efficacy and safety of guaifenesin for upper back,
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4: Deng S, Huang W, Ni X, Zhang M, Lu H, Wang Z, Hu J, Zhu X, Qiu C, Shang D,
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5: Kolbach-Mandel AM, Mandel NS, Cohen SR, Kleinman JG, Ahmed F, Mandel IC,
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8: Melegari C, Bertoni S, Genovesi A, Hughes K, Rajabi-Siahboomi AR, Passerini N,
Albertini B. Ethylcellulose film coating of guaifenesin-loaded pellets: A
comprehensive evaluation of the manufacturing process to prevent drug migration.
Eur J Pharm Biopharm. 2016 Mar;100:15-26. doi: 10.1016/j.ejpb.2015.12.001. Epub
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9: Thompson GA, Solomon G, Albrecht HH, Reitberg DP, Guenin E. Guaifenesin
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10: Yehia AM, Mohamed HM. Chemometrics resolution and quantification power
evaluation: Application on pharmaceutical quaternary mixture of Paracetamol,
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