GSK1292263

• CAT Number: I000196
• CAS Number: 1032823-75-8
• Molecular Formula: C23H28N4O4S
• Molecular Weight: 456.56
• Purity: ≥95%
• Target: Free Fatty Acid Receptors
• Solubility: DMSO ≥22mg/mL Water <1.2mg/mL Ethanol ≥1.8mg/mL
• Storage: Store at -20°C
• IUPAC Name: 5-[4-[[6-(4-methylsulfonylphenyl)pyridin-3-yl]oxymethyl]piperidin-1-yl]-3-propan-2-yl-1,2,4-oxadiazole
• InChI: InChI=1S/C23H28N4O4S/c1-16(2)22-25-23(31-26-22)27-12-10-17(11-13-27)15-30-19-6-9-21(24-14-19)18-4-7-20(8-5-18)32(3,28)29/h4-9,14,16-17H,10-13,15H2,1-3H3
• InChIKey: AYJRTVVIBJSSKN-UHFFFAOYSA-N
• SMILES: CC(C)C1=NOC(=N1)N2CCC(CC2)COC3=CN=C(C=C3)C4=CC=C(C=C4)S(=O)(=O)C

GSK1292263（Cat No.:I000196）, is a chemical compound of interest in pharmacology and drug research. It serves as a selective inhibitor, primarily targeting a specific protein or pathway in biological systems. The exact mechanisms and therapeutic applications of GSK1292263 may vary depending on specific research studies, but it is often employed to explore and understand the roles of specific molecular targets within cells.

Reference

1:Gut hormone pharmacology of a novel GPR119 agonist (GSK1292263), metformin, and sitagliptin in type 2 diabetes mellitus: results from two randomized studies. Nunez DJ, Bush MA, Collins DA, McMullen SL, Gillmor D, Apseloff G, Atiee G, Corsino L, Morrow L, Feldman PL.PLoS One. 2014 Apr 3;9(4):e92494. doi: 10.1371/journal.pone.0092494. eCollection 2014. PMID: 24699248 Free PMC Article2:Evaluation of drug interactions of GSK1292263 (a GPR119 agonist) with statins: from in vitro data to clinical study design. Polli JW, Hussey E, Bush M, Generaux G, Smith G, Collins D, McMullen S, Turner N, Nunez DJ.Xenobiotica. 2013 Jun;43(6):498-508. doi: 10.3109/00498254.2012.739719. Epub 2012 Dec 21. PMID: 23256625