Gossypin

  • CAT Number: I012084
  • CAS Number: 652-78-8
  • Molecular Formula: C21H20O13
  • Molecular Weight: 480.37
  • Purity: ≥95%
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Gossypin (Cat.No:I012084) is a glucoside occurring in cotton and Hubiscus flowers that acts as a potent antimelanoma agent. Gossypin inhibits human melanoma cell proliferation, in vitro, in melanoma cell lines that harbors both BRAF-V600E kinase and CDK4 as well as in cells with BRAF wild-type allele. Gossypin inhibits the kinase activities of BRAF-V600E and CDK4, in vitro, possibly through direct binding with these kinases.

Catalog Number I012084
CAS Number 652-78-8
Synonyms

3,3/’,4/’,5,7,8-Hexahydroxyflavone-8-glucoside

Molecular Formula

C21H20O13

Purity 95%
Target A potent antimelanoma agent
Solubility DMSO
Storage Store at -20 ̊C
IUPAC Name 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
InChI InChI=1S/C21H20O13/c22-5-11-13(27)15(29)17(31)21(32-11)34-19-10(26)4-9(25)12-14(28)16(30)18(33-20(12)19)6-1-2-7(23)8(24)3-6/h1-4,11,13,15,17,21-27,29-31H,5H2/t11-,13-,15+,17-,21+/m1/s1
InChIKey SJRXVLUZMMDCNG-KKPQBLLMSA-N
SMILES C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O)O

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